The NIHR i4i Programme, in collaboration with the Office for Life Sciences (OLS), invites applications to the Cancer Mission: Early Cancer Diagnosis Clinical Validation and Evaluation Call.
Award: Share of up to £1.5 million
Opens: 24th Oct 2023
Closes: 12th Dec 2023
The NIHR i4i Programme, in collaboration with the Office for Life Sciences (OLS), invites applications to the Cancer Mission: Early Cancer Diagnosis Clinical Validation and Evaluation Call. Proposals must demonstrate how the selected innovation will increase the proportion of cancers diagnosed at stages 1 and 2. Proposals aiming to directly address health inequalities in stage of cancer diagnosis are particularly sought.
The Cancer Mission: Early Cancer Diagnosis Clinical Validation and Evaluation Call is a one-stage call inviting applications for projects up to 36 months in duration, with no upper funding limit.
The call will be open to organisations which are UK legal entities, that have an innovative solution with the potential to increase the proportion of cancers diagnosed at stages 1 and 2. This call is open to small/medium commercial entities, NHS and Third Sector Service Providers, charitable organisations, local government bodies, as well as universities and research institutions.
The aim of the call is to support the clinical validation and evaluation of breakthrough technologies that can increase the proportion of cancers which are detected earlier in the disease course and/or target health inequalities in stage of cancer diagnosis.
Funding will be deployed to facilitate the generation of evidence on safety, test performance characteristics, clinical efficacy and/or effectiveness that can support regulatory approvals requirements and subsequent clinical implementation or implementation research.
The expected objectives of this investment are to:
Types of eligible innovations include, but are not limited to, medical devices, in vitro diagnostics, NICE classified Tier C digital health solutions, software, artificial intelligence, behavioural interventions and new models of care.
Applicants may wish to consider the following (non-exclusive) potential solutions to improving early diagnosis of cancer:
Funding is available for validation and evaluation of the potential to detect and diagnose earlier, in an NHS setting, either directly in individuals or in samples/data taken from these.
This can include, but is not limited to, funding for:
Though not limited to these approaches, this call could be suitable for:
For further information on this funding call, please see here
Applicants are welcome from:
Specialist services or expertise may be brought into the team through consultancy or sub-contract arrangements with appropriate justification. Collaborators and sub-contractors may be based outside of the UK if the required expertise or service cannot be reasonably contracted from within the UK. Involvement of international companies as subcontractor and/or collaborator, if working with a lead UK partner, are welcomed.
Applicants must review the NIHR standard research contract before application submission and agree in principle with its core terms and conditions as they are non-negotiable.
Applicant organisations can be based anywhere in the UK, and the proposed research must take place in the UK and show potential, and be appropriate, for roll out across the UK.
To support the growth of innovators in this field, applications from early career researchers and innovators are particularly welcomed. They can apply as either the lead or joint-lead applicant together with a senior colleague fulfilling the other role.
Consultation with individuals who have current or lived experience is expected.
Multidisciplinary project teams, involving relevant collaborations between technology developers, data scientists and clinical staff, are particularly welcome. The lead organisation should be best placed among the project parties, to lead the research, and either own or have full access to the background IP.
The call encourages proposals putting forward innovative solutions. To support this, there is no upper funding limit. Proposed projects may be of up to 36 months in duration.
We would expect the majority of applications to request up to £1.5m funding, however applicants are discouraged from compromising their ideas to meet this guideline, and applications will be considered on the overall merit and value for money they provide. Proposals may request smaller or larger funding amounts that reflect the scope and duration of the proposed project. Each proposal will be judged on its merits and value for money.
NIHR funding covers 100% costs for commercial entities, not-for-profit organisations, local government bodies, and primary care providers: 100% of the direct research costs for NHS service providers, and 80% FEC for higher education institutions.
Support with research design and forging partnerships is available to all prospective applicants through the NIHR research support services, detailed below. All prospective applicants are encouraged to engage with these services at the earliest opportunity.
If you are considering applying and you are new to research or are not from a research institution, please do contact the appropriate NIHR research support services for free advice and support in finding potential research partners. This support is also available for experienced researchers, free of charge.
* Please note that the RSS service is only available to applicants based in England. Applicants with a project partner based in England are able to access the service, but if you are based in the UK but outside of England and are not partnered with an organisation based in England you may wish to explore the below services. The NIHR Business Development Team is available to all UK based applicants, and you may wish to contact them in seeking a partner based in England.
Other organisations that may be able to support projects include:
For any enquiries email: firstname.lastname@example.org
Book an appointment to speak to one of our advisors to discuss your eligibility to apply for this Grant Funding opportunity.